ITM2B anticorps

N° du produit ABIN2723906

Cet anticorps Souris Monoclonal détecte spécifiquement ITM2B dans WB, IHC et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour ITM2B anticorps (ABIN2723906)

Antigène: ITM2B (Integral Membrane Protein 2B (ITM2B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITM2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 1C11

Détail du produit anti-ITM2B anticorps

Attributs du produit: Homo sapiens integral membrane protein 2B (ITM2B)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human ITM2B (NP_068839) produced in HEK293T cell.

Isotype: IgG2a

Information d'application

Indications d'application: WB 1:2000, IHC 1:150, FLOW 1:100

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur ITM2B

Antigène: ITM2B (Integral Membrane Protein 2B (ITM2B))

Autre désignation: ITM2B

Sujet: Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.

Poids moléculaire: 30.2 kDa

ID gène: 9445

NCBI Accession: NM_021999

HGNC: 9445